Tetrahedron

Facile synthesis of novel 7-aminofuro-and 7-aminothieno [2, 3-d] pyridazin-4 (5H)-one and 4-aminophthalazin-1 (2H)-ones

G Koza, S Keskin, MS Özer, B Cengiz, E Şahin, M Balci

Index: Koza, Gani; Keskin, Selbi; Oezer, Merve Sinem; Cengiz, Betuel; Sahin, Ertan; Balci, Metin Tetrahedron, 2013 , vol. 69, # 1 p. 395 - 409

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Citation Number: 14

Abstract

We hereby report the synthesis of a novel class of compounds, 7-aminofuro-and 7- aminothieno [2, 3-d] pyridazin-4 (5H)-one and 4-aminophthalazin-1 (2H)-ones starting from methyl 2-(2-methoxy-2-oxoethyl) furan-and thiophene-3-carboxylate and methyl 2-(2- methoxy-2-oxoethyl) benzoate. The ester functionalities connected directly to the aromatic ring were regiospecifically converted to the acid, whereas methylene groups were ...

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Facile synthesis of novel 7-aminofuro-and 7-aminothieno [2, 3-d] pyridazin-4 (5H)-one and 4-aminophthalazin-1 (2H)-ones

[Tetrahedron, , vol. 69, # 1 p. 395 - 409]

Facile synthesis of novel 7-aminofuro-and 7-aminothieno [2, 3-d] pyridazin-4 (5H)-one and 4-aminophthalazin-1 (2H)-ones

[Tetrahedron, , vol. 69, # 1 p. 395 - 409]

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