Studies towards the synthesis of the benzodiazepine alkaloid auranthine
A Witt, A Gustavsson, J Bergan
Index: Witt, Anette; Gustavsson, Annika; Bergman, Jan Journal of Heterocyclic Chemistry, 2003 , vol. 40, # 1 p. 29 - 35
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Citation Number: 12
Abstract
Abstract Different approaches towards the synthesis of auranthine have been investigated. A completed synthesis of 3-[2-(4-oxo-3, 4-dihydro-quinazolin-2-yl)-3, 4-dihydro-1H-benzo [e][1, 4]-diazepine-2, 5-dione, an auranthine precursor, which after dehydration with 50% propylphophonic acid anhydride solution in ethl acetate and DMA gave a C-acetyl derivative of aurnathine. Additionally studies towards the synthesis of fused quinazolinones yielded ...
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