A concise synthesis of photoactivatable 4-Aroyl-l-phenylalanines

E Morera, G Ortar

Index: Morera, Enrico; Ortar, Giorgio Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 16 p. 1815 - 1818

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Citation Number: 19

Abstract

The use of benzophenone (BP) photophores in biochemistry has increased considerably during the past 10 years, owing to their advantages over previously employed diazoester, azide, and diazirine probes. 1 In particular, the development of 4-benzoyl-l-phenylalanine (BPA, 1a), 2 a BP-containing amino acid, brought a significant advance in the application of photoaffinity labeling to the study of peptide–protein interactions. ... Aryl iodides can be carbonylatively ...