Gallium (III)-catalysed bromocyanation of alkynes: regio-and stereoselective synthesis of β-bromo-α, β-unsaturated nitriles

M Murai, R Hatano, S Kitabata, K Ohe

Index: Murai, Masahito; Hatano, Ryo; Kitabata, Sachie; Ohe, Kouichi Chemical Communications, 2011 , vol. 47, # 8 p. 2375 - 2377

Full Text: HTML

Citation Number: 29

Abstract

The catalytic addition reactions of X–Y-type substrates to carbon–carbon multiple bonds are of continued interest due to the facile access to 1,2-difunctional units from simple alkenes or alkynes with ideal atom efficiency. 1 Among these transformations, addition reactions of X–CN to alkynes simultaneously form vinyl–X and vinyl–carbon bonds, both of which can be used to construct complex structures. Several notable examples of palladium- or nickel-catalysed ...