Total Synthesis of (+)??Cortistatin A

KC Nicolaou, YP Sun, XS Peng, D Polet…

Index: Nicolaou; Sun, Ya-Ping; Peng, Xiao-Shui; Polet, Damien; Chen, David Y.-K. Angewandte Chemie - International Edition, 2008 , vol. 47, # 38 p. 7310 - 7313

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Citation Number: 83

Abstract

Angiogenesis is an important physiological phenomenon whose imbalance may result in several disease states, including malignant, inflammatory, ischaemic, infectious, and immune disorders.[1] The inhibition of angiogenesis has been considered for some time as an attractive way to improve such conditions. With the recent introduction of the first antiangiogenic agents to treat cancer and blindness, the search for new inhibitors of ...