Trihaloisocyanuric acids as convenient reagents for regioselective halogenation of β-dicarbonyl compounds

GF Mendonça, HC Sindra, LS de Almeida…

Index: Mendonca, Gabriela F.; Sindra, Haryadylla C.; de Almeida, Leonardo S.; Esteves, Pierre M.; de Mattos, Marcio C.S. Tetrahedron Letters, 2009 , vol. 50, # 4 p. 473 - 475

Full Text: HTML

Citation Number: 42

Abstract

The reaction of β-dicarbonyl compounds (β-ketoesters and β-diketones) with 0.34 molequiv of trichloro-and tribromoisocyanuric acids produced regioselectively the corresponding α- monohalo β-dicarbonyl compound. On the other hand, utilization of 0.68 molequiv of the trihaloisocyanuric acid produced the α, α-dihalo β-dicarbonyl compound.