The synthesis of an amine-bearing polymerizable phospholipid

…, E Stalder, IA Fedotenko, F Favarger, A Zumbuehl

Index: Zaffalon, Pierre-Leonard; Stalder, Etienne; Fedotenko, Illya A.; Favarger, France; Zumbuehl, Andreas Tetrahedron Letters, 2011 , vol. 52, # 32 p. 4215 - 4217

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Citation Number: 3

Abstract

Abstract Exchange of the natural glycerol phospholipid backbone with an artificial 1, 3- diaminopropanol backbone led to the first synthetic 1, 3-diaminophospholipid. The amines in the polar head group region were reacted to acrylamides giving a UV polymerizable phospholipid. Preliminary experiments demonstrate that formulated vesicles can be polymerized into large aggregates of vesicles.