The cleavage of oxazolidines by lithium aluminum hydride

ED Bergmann, D Lavie, S Pinchas

Index: Bergmann et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 5662

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Citation Number: 19

Abstract

Lithium aluminum hydride cleaves the oxazolidine ring between the 1-and 2-positions, leading to N-substituted 2amino-alkanols, when the nitrogen atom is unsubstituted, and to N, N-disubstituted 2-aminoalkanols, when it is substituted. In this respect, lithium aluminum hydride resembles catalytically activated hydrogen and Grignard compounds.