Tetrahedron Letters

Chemical conversion of arachidonic acid to slow reacting substances

EJ Corey, AE Barton

Index: Corey, E. J.; Barton, Alan E. Tetrahedron Letters, 1982 , vol. 23, # 23 p. 2351 - 2354

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Citation Number: 27

Abstract

Abstract The synthesis of slow reacting substances, leukotrienes C, D, and E, can be accomplished conveniently by a stereoselective biomimetic route. Details are provided for the conversion of 5-HPETE methyl ester 4 to leukotriene methyl ester (2) and thence to