Stereospecific synthesis of 2-deoxy-2, 2-difluororibonolactone and its use in the preparation of 2′-deoxy-2′, 2′-difluoro-β-D-ribofuranosyl pyrimidine nucleosides: …

TS Chou, PC Heath, LE Patterson, LM Poteet…

Index: Synthesis, , # 6 p. 565 - 570

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Citation Number: 81

Abstract

... rimidine nucleosides such as 2'-deoxy-2',2'-difiuorouridine (19) were synthesized for structure ... We utilized the same synthetic scheme but selected benzoyl over tert-butyldimethylsilyl as the ... thus the benzoyl protecting group indeed occupies an unique place in this synthesis. ...