Preparation, antibacterial effects and enzymatic degradation of 5-fluorouracil nucleosides

B Schwarz, D Cech, A Holý…

Index: Schwarz; Cech; Holy; Skoda Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 11 p. 3217 - 3230

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Citation Number: 11

Abstract

Abstract Reaction of perbenzoylated aldopentafuranosyl derivatives of uracil with fluorine in acetic acid afforded perbenzoylated 5-fluorouracil nucleosides. Their methanolysis gave the following free nucleosides of 5-fluorouracil: β-D-ribofuranoside (Id), 2-deoxy-β-D- ribofuranoside (IId), their enantiomers VIII and IX, α-D-ribofuranoside (XIII), 2-deoxy-α-D- ribofuranoside (XV), β-D-arabinofuranoside (IV) and its L-enantiomer X, β-D- ...