The Mechanism of Halide Reductions with Lithium Aluminum Hydride. IV. Tracer Studies in the Reduction of Halohydrins1

EL Eliel, TJ Prosser

Index: Eliel; Prosser Journal of the American Chemical Society, 1956 , vol. 78, p. 4045,4048

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Citation Number: 26

Abstract

2-Bromo-1-butanol, 2-chloro-2-methylpropanol and 2-chloro-2-phenylethanol have been reduced to the corresponding alcohols 1-butanol, 2-methyl-1-propanol and 2-phenylethanol with lithium aluminum hydride in ether solution. Thi.; strengthens the assumption made in previous papers in this series that the halohydrins are intermediates in the reduction of the corresponding a-haloacids to alcohols. Reduction of the halohydrins is facilitated by the ...