Tetrahedron letters

Synthesis of β-aminosulfonopeptides activated through selective N-nitration of a taurine amide unit

S Paik, EH White

Index: Paik, Seunguk; White, Emil H. Tetrahedron Letters, 1996 , vol. 37, # 27 p. 4663 - 4666

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Citation Number: 16

Abstract

β-Sulfonopeptides bearing a taurine in place of a penultimate amino acid unit were designed and synthesized as inhibitors of D-alanyl-D-alanine transpeptidases; N-nitration of the sulfonamide bond in the presence of multiple carboxamide groups was selectively accomplished through use of NO2BF4.