Improved method for the isolation of geranyl esters of (4E/Z, 8E)-and (4E/Z, 8Z)-farnesylacetic acid

…, P Serebryakov, LA Yanovskaya

Index: Nigmatov, A. G.; Serebryakov, E. P.; Yanovskaya, L. A. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 7 p. 529 - 533 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 7 p. 854 - 858

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Abstract

The geranyl esters of 4E, 8E-farnesylacetic acid and its stereomers are effective agents for the prophylaxis and treatment of gastric ulcers [i0]. The synthesis utilizing malonic ester is a simple method for the isolation of these compounds [6, 8]. We improved this principal

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