Determination of the complete absolute configuration of petriellin A

L Aurelio, RTC Brownlee, J Dang, AB Hughes…

Index: Aurelio, Luigi; Brownlee, Robert T. C.; Dang, Jason; Hughes, Andrew B.; Polya, Gideon M. Australian Journal of Chemistry, 2006 , vol. 59, # 6 p. 407 - 414

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Citation Number: 5

Abstract

Abstract We report the full structural determination of the depsipeptide petriellin A. The absolute configuration of the amino acid residues, N-methyl isoleucine and N-methyl threonine, have been determined by a combination of HPLC and TLC comparison of synthetic Marfey's derivatives and Marfey's derivatives of the natural product hydrolysate. The configuration of the chiral centres in these two N-methylated residues was found to be ...

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