Production of monoclonal antibodies to the prion protein and their characterization

…, AA Egorov, SS Rybakov, OM Vol'pina

Index: Russian Journal of Bioorganic Chemistry, , vol. 21, # 9 p. 582 - 589 Bioorganicheskaya Khimiya, , vol. 21, # 9 p. 675 - 685

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Abstract

Abstract Antibodies to the prion protein (PrP), particularly, monoclonal antibodies, are necessary tools in the diagnostics and study of prion diseases and potential means of their immunotherapy. For the production of monoclonal antibodies, BALB/c mice were immunized