Water??Compatible Iminium Activation: Organocatalytic Michael Reactions of Carbon??Centered Nucleophiles with Enals

…, A Mielgo, M Oiarbide, A Puente, S Vera

Index: Palomo, Claudio; Landa, Aitor; Mielgo, Antonia; Oiarbide, Mikel; Puente, Angel; Vera, Silvia Angewandte Chemie - International Edition, 2007 , vol. 46, # 44 p. 8431 - 8435

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Citation Number: 182

Abstract

Water offers unique characteristics as a solvent. It displays unparalleled physical properties, is cheap, available in bulk, and hazardless in handling, and overall it sustains life and therefore most biosynthetic reactions. In the practice of chemical synthesis, however, water had been considered a contaminant for a while. Over the last few decades, chemists have started to investigate the possibility of using water as solvent for organic reactions [1] ...

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