Tetrahedron Letters

Design, synthesis and anti-influenza virus activities of terminal modified antisense oligonucleotides

J Zhang, D Lu, A Li, J Yang, S Wang

Index: Zhang, Jingyu; Lu, Dandan; Li, Aixing; Yang, Jing; Wang, Shengqi Tetrahedron Letters, 2014 , vol. 55, # 1 p. 94 - 97

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Abstract

Abstract Four novel terminal modified antisense oligonucleotides (ODNs) were designed, synthesized and tested for their anti-influenza virus activity. Initial biological studies indicated that lipophilic and rimantadin emodificated Flutide exhibited more potent anti- ...