Tetrahedron

An easy access to trisubstituted vinyl chlorides and improved synthesis of chloro/bromostilbenes

C Muthiah, KP Kumar, S Kumaraswamy, KCK Swamy

Index: Muthiah; Kumar, K. Praveen; Kumaraswamy, Sudha; Kumara Swamy Tetrahedron, 1998 , vol. 54, # 47 p. 14315 - 14326

Full Text: HTML

Citation Number: 18

Abstract

The α-chlorophosphonates (OCH2CMe2CH2O) P (O) CHCl-C6H4-4-R [R= H (4), Me (5), OMe (6)], which are now readily accessible, react with ketones R′ C (O) R ″in the presence of NaH (without recourse to the more expensive t-BuLi) to afford trisubstituted vinyl halides R′ C (R ″)= CCl (C6H4-4-R) in good yields. The corresponding α- bromophosphonates [R= H (7), Me (8)] failed to react with ketones and gave the ...

Related Articles:

A Single-Step Synthesis of Enynes: Pd-Catalyzed Arylalkynylation of Aryl Iodides, Internal Alkynes, and Alkynylsilanes

[Sakai, Norio; Komatsu, Ryosuke; Uchida, Naoki; Ikeda, Reiko; Konakahara, Takeo Organic Letters, 2010 , vol. 12, # 6 p. 1300 - 1303]

One-pot synthesis of 1, 4-diarylsubstituted 1, 3-diynes from the sequential coupling reactions of aryl iodides and propiolic acid

[Kim, Yong; Park, Ahbyeol; Park, Kyungho; Lee, Sunwoo Tetrahedron Letters, 2011 , vol. 52, # 15 p. 1766 - 1769]

Calcium carbide as a cost-effective starting material for symmetrical diarylethynes via Pd-catalyzed coupling reaction

[Chuentragool, Padon; Vongnam, Kunnigar; Rashatasakhon, Paitoon; Sukwattanasinitt, Mongkol; Wacharasindhu, Sumrit Tetrahedron, 2011 , vol. 67, # 42 p. 8177 - 8182]

The use of calcium carbide in one-pot synthesis of symmetric diaryl ethynes

[Zhang, Weiwei; Wu, Huayue; Liu, Zhiqing; Zhong, Ping; Zhang, Lin; Huang, Xiaobo; Cheng, Jiang Chemical Communications, 2006 , # 46 p. 4826 - 4828]

Publikációs lista–Kotschy András A, Könyv, könyvfejezet

[Yi, Chenyi; Hua, Ruimao; Zeng, Hanxiang; Huang, Qiufeng Advanced Synthesis and Catalysis, 2007 , vol. 349, # 10 p. 1738 - 1742]

More Articles...