ChemCatChem

Tandem Synthesis of N??Alkylated Amides from Aldoximes and Alcohols by Using a Ru/Ir Dual??Catalyst System

F Li, P Qu, J Ma, X Zou, C Sun

Index: Li, Feng; Qu, Panpan; Ma, Juan; Zou, Xiaoyuan; Sun, Chunlou ChemCatChem, 2013 , vol. 5, # 8 p. 2178 - 2182

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Citation Number: 26

Abstract

N-alkylated amides constitute an important class of nitrogencontaining compounds that are widely utilized in fine chemicals, natural products, pharmaceuticals, peptides, and polymers.[1] Traditionally, N-alkylated amides are synthesized by the coupling of carboxylic acids or their derivatives (eg, acid chlorides, anhydrides, and esters) with N-alkylated amines.[2] In addition, the Beckmann rearrangement,[3] the Schmidt rearrangement,[4] ...

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