Organocatalytic sequential one-pot double cascade asymmetric synthesis of Wieland-Miescher ketone analogues from a Knoevenagel/Hydrogenation/Robinson …
DB Ramachary, M Kishor
Index: Jaxa-Chamiec, Albert A.; Sammes, Peter G.; Kennewell, Peter D. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 170 - 175
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Citation Number: 133
Abstract
... The Journal of Organic ... 14f,g As shown in Scheme 1, the well-recognized fact is the inability to arrest Knoevenagel reactions involving CH acids 1 ... ester 3 through self-catalysis by decreasing the HOMO−LUMO energy gap between olefins and Hantzsch ester 3, 4b-d we initiated ...
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