Synthesis of 6-and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline

HT Pham, RN Hanson, SL Olmsted, A Kozhushnyan…

Index: Tetrahedron Letters, , vol. 52, # 10 p. 1053 - 1056

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Citation Number: 4

Abstract

... Tetrahedron Letters. Volume 52, Issue 10, 9 March 2011, Pages 1053–1056. ... borohydride-nickel chloride were reasonably successful on larger scale (10–20 mmol) reductions to give the anilines 7 and 8. Cyclization of the anilines to the quinazolin-4-ones 9 and 10 was achieved ...

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