Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4

JP Powers, S Li, JC Jaen, J Liu, NPC Walker…

Index: Powers, Jay P.; Li, Shyun; Jaen, Juan C.; Liu, Jinqian; Walker, Nigel P.C.; Wang, Zhulun; Wesche, Holger Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 11 p. 2842 - 2845

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Citation Number: 77

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4. ... High-throughput screening of a small-molecule compound library resulted in ...