Tetrahedron

Researches on antiviral agents. 4. Studies on the chemistry of 6-methyl-2-methoxy-4-O-acyloxy and 6-methyl-2, 4-di-O-acyloxypyrimidine derivatives as new acylation …

M Botta, R Saladino, G Gentile, V Summa, R Nicoletti…

Index: Botta; Saladino; Gentile; Summa; Nicoletti; Verri; Focher; Spadari Tetrahedron, 1994 , vol. 50, # 11 p. 3603 - 3618

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Citation Number: 13

Abstract

The synthesis of 6-methyl-2-methoxy-4-O-acyloxy and 6-methyl-2, 4-di-O-acyloxypyrimidine derivatives 2 and 5 along with their properties as acylating agents of amines, alcohols, thiols and α-amino acids have been reported. Interestingly some of the title products revealed an inhibitory activity against the human and herpetic DNA glycosylases.

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