Oxidative Amidation of Aldehydes and Alcohols with Primary Amines Catalyzed by KI??TBHP

…, CU Maheswari, M Venkateshwar…

Index: Rajender Reddy; Uma Maheswari; Venkateshwar; Lakshmi Kantam European Journal of Organic Chemistry, 2008 , # 21 p. 3619 - 3622

Full Text: HTML

Citation Number: 59

Abstract

Abstract Oxidative amidation of aldehydes and alcohols with amines to afford the corresponding amides in excellent yields and ee values over 98% is achieved by using a catalytic amount of KI in combination with TBHP as the external oxidant. This method avoids the use of expensive and/or air-sensitive reagents.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

Related Articles:

Solvent free, N, N′-carbonyldiimidazole (CDI) mediated amidation

[Verma, Sanjeev K.; Ghorpade, Ramarao; Pratap, Ajay; Kaushik Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2373 - 2376]

Recueil des Travaux Chimiques des Pays??Bas Journal of the Royal Netherlands Chemical Society: General method for the synthesis of 3′, 5′??diesters and 2′?? …

[Fache, Fabienne; Bethmont, Valerie; Jacquot, Laurent; Lemaire, Marc Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands, 1996 , vol. 115, # 4 p. 231 - 238]

O-Succinimidyl-1, 3-dimethyl-1, 3-trimethyleneuronium salts as efficient reagents in active ester synthesis

[Bailen, Miguel A; Chinchilla, Rafael; Dodsworth, David J; Najera, Carmen Tetrahedron Letters, 2002 , vol. 43, # 9 p. 1661 - 1664]

Zinc oxide (ZnO) as a new, highly efficient, and reusable catalyst for acylation of alcohols, phenols and amines under solvent free conditions

[Hosseini Sarvari, Mona; Sharghi, Hashem Tetrahedron, 2005 , vol. 61, # 46 p. 10903 - 10907]

Direct transacylation of 2, 2, 2-trihaloethyl esters with amines and alcohols using phosphorus (III) reagents for reductive fragmentation and in situ activation

[Hans, Jeremy J.; Driver, Russell W.; Burke, Steven D. Journal of Organic Chemistry, 2000 , vol. 65, # 7 p. 2114 - 2121]

More Articles...