Electrophilic ipso substitution of trimethylsilyl groups in fluorobenzenes

PL Coe, AM Stuart, DJ Moody

Index: Coe, Paul L.; Stuart, Alison M.; Moody, David J. Journal of Fluorine Chemistry, 1998 , vol. 92, # 1 p. 27 - 32

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Citation Number: 14

Abstract

Using variants of literature methods 2, 4-and 2, 6-difluorophenyltrimethylsilanes have been bromodesilylated to the corresponding bromodifluorobenzenes in moderate to good yields, 3-bromo-2, 6-difluorophenyltrimethylsilane afforded 1, 3-dibromo-2, 4-difluorobenzene whilst 1, 3-difluoro-2, 4-bis (trimethylsilyl) benzene yielded 3-bromo-2, 6- difluorophenyltrimethylsilane. Application of either the Eaborn or Chvalovsky methods of ...