Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors

MA Cinelli, A Morrell, TS Dexheimer…

Index: Roglans; Marquet; Moreno-Manas Synthetic Communications, 1992 , vol. 22, # 9 p. 1249 - 1258

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Citation Number: 52

Abstract

... Volume: Page ... inhibitors is effectively a “composite” of the natural products camptothecin and luotonin A and the synthetic indenoisoquinolines ... As reported in the present communication, a new series of 14-substituted aromathecins have been synthesized via two ...