Tetrahedron Letters

Indium-HI-mediated one-pot reaction of 1-(2-arylethynyl)-2-nitroarenes to 2-arylindoles

JS Kim, JH Han, JJ Lee, YM Jun, BM Lee, BH Kim

Index: Kim, Ji Sook; Han, Joon Hee; Lee, Jung June; Jun, Young Moo; Lee, Byung Min; Kim, Byeong Hyo Tetrahedron Letters, 2008 , vol. 49, # 23 p. 3733 - 3738

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Citation Number: 20

Abstract

While 1-(2-arylethynyl)-2-nitroarenes were reduced to 2-(2-arylethynyl) anilines in the presence of indium and InCl3 in THF/H2O (v/v= 5/1) at 50° C, 1-(2-arylethynyl)-2-nitroarenes were reductively cyclized to 2-arylindoles with good yields in the presence of indium and aqueous HI in benzene.

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