Journal of Fluorine Chemistry

Catalyst free 1, 3-dipolar cycloaddition of 3-oxo-1, 2-pyrazolidinium ylides to β-trifluoroacetyl vinyl ethyl ether: Synthesis of 6-trifluoroacetyl substituted bicyclic …

Y Xin, J Zhao, J Gu, S Zhu

Index: Xin, Yong; Zhao, Jingwei; Gu, Jiwei; Zhu, Shizheng Journal of Fluorine Chemistry, 2011 , vol. 132, # 6 p. 402 - 408

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Citation Number: 13

Abstract

Abstract A catalyst free cycloaddition reaction of 3-oxo-1, 2-pyrazolidinium ylides with β- trifluoroacetyl vinyl ethyl ether is reported, which proceeded smoothly at ambient temperature and afford the bicyclic pyrazolidinone products in good yield. This is the first report of synthesis of 6-trifluoroacetyl substituted bicyclic pyrazolidinones that are potentially anti-microbial and herbicidal.