A stereoselective route to cis-2-phenyl-3-piperidinol
N Liang, P Srinivas, A Datta
Index: Liang, Ningning; Srinivas, Pusuluri; Datta, Apurba Tetrahedron Letters, 2005 , vol. 46, # 42 p. 7221 - 7223
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Citation Number: 4
Abstract
Enantiopure cis-2-phenyl-3-piperidinol is a commonly used synthon for the obtention of a potent class of neurokinin substance P receptor antagonists. Starting from (R)- phenylglycine, the present report describes an efficient route for the stereoselective synthesis of the above piperidinol structural core.
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