Effect of the ortho modification of azobenzene on the photoregulatory efficiency of DNA hybridization and the thermal stability of its cis form

H Nishioka, X Liang, H Asanuma

Index: Nishioka, Hidenori; Liang, Xingguo; Asanuma, Hiroyuki Chemistry - A European Journal, 2010 , vol. 16, # 7 p. 2054 - 2062

Full Text: HTML

Citation Number: 32

Abstract

Abstract We synthesized various azobenzenes methylated at their ortho positions with respect to the azo bond for more effective photoregulation of DNA hybridization. Photoregulatory efficiency, evaluated from the change of T m (ΔT m) induced by trans–cis isomerization, was significantly improved for all ortho-modified azobenzenes compared with non-modified azobenzene due to the more stabilized trans form and the more destabilized ...