Tetrahedron

Synthesis of novel fused azecine ring systems through application of the tert-amino effect

P Dunkel, G Túrós, A Bényei, K Ludányi, P Mátyus

Index: Dunkel, Petra; Turos, Gyoergy; Benyei, Attila; Ludanyi, Krisztina; Matyus, Peter Tetrahedron, 2010 , vol. 66, # 13 p. 2331 - 2339

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Citation Number: 41

Abstract

Novel fused azecine ring systems were synthesized via the microwave-assisted thermal isomerization of terphenyl or biphenyl-pyridazine compounds possessing a vinyl and a tert- amino group, through application of a new extension of the tert-amino effect. Substrates for the ring closure were prepared from ortho-dihalobenzene or pyridazinone by consecutive Suzuki couplings with ortho-sec-amino-and formylphenylboronic acids, followed by ...