Trichodiene synthase. Synergistic inhibition by inorganic pyrophosphate and aza analogs of the bisabolyl cation.

DE Cane, G Yang, RM Coates, HJ Pyun…

Index: Cane, David E.; Yang, Guohan; Coates, Robert M.; Pyun, Hyung-Jung; Hohn, Thomas M. Journal of Organic Chemistry, 1992 , vol. 57, # 12 p. 3454 - 3462

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Citation Number: 51

Abstract

X lo' L mol-' cm-'); CTP A- 275 nm (e 6.6 X 103 L mol-' cm-'); dd?TP and AzlTp A- 268 nm (e 8.4 X 103 L mot1 cm-I). The extraction yields in Table I1 are averages of triplicate rune. Acknowledgment. We thank the National Institutes of Health (Grant GC-R-123558) for the support of this work. ... Trichodiene Synthase. Synergistic Inhibition by Inorganic Pyrophosphate and Aza Analogs of the Bisabolyl Cation ... Department of Chemistry, Box H, Brown ...

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