Chemical communications

New synthesis of 1, 4-diketones via rhodium-catalysed 1, 4 carbonylative addition of arylboronic acids to α, β-unsaturated ketones

M Sauthier, Y Castanet, A Mortreux

Index: Sauthier, Mathieu; Castanet, Yves; Mortreux, Andre Chemical Communications, 2004 , # 13 p. 1520 - 1521

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Citation Number: 18

Abstract

1,4-diketones are very useful intermediates for thienyl, pyrrol or furyl heterocycles synthesis. 1 A synthetic pathway for this family of derivatives is the acylation reaction of α,β-unsaturated ketones. 2 For this purpose, early acylmetal reagents were only partially successful. They often suffer from the use of toxic metal carbonyl complexes and/or stoichiometric amounts of metal. Moreover, even used in combination with a palladium catalyst these acyl sources ...

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