Journal of the American Chemical Society

Cyclization of Acylaminoalkanols to 2-Oxazolines1

RN Boyd, RC Rittner

Index: Boyd,R.N.; Rittner,R.C. Journal of the American Chemical Society, 1960 , vol. 82, p. 2032 - 2034

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Citation Number: 14

Abstract

Through the use of o-toluenesulfonyl chloride and pyridine it has been found possible to form 2-oxazolines from acylaminonlkanols in which the amido group is attached to primary, secondary or tertiary carbon, and the alcohol is primary or secondary. The yield of oxazoline ranged from 21-85y0 depending upon the structure of the ncylaminoalkanol. Sulfonic acid esters are suggested as intermediates.

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