Synlett

A convenient one-pot PCC oxidation-wittig reaction of alcohols

AR Bressette, LC Glover Iv

Index: Bressette, Andrew R.; Glover IV, Louis C. Synlett, 2004 , # 4 p. 738 - 740

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Citation Number: 17

Abstract

Alcohols hold a central position in synthesis as they are easily converted to a multitude of functional groups through many rapid, facile transformations. One such transformation frequently employed is the oxidation of primary and secondary alcohols followed by coupling of the carbonyl [1] with a Wittig reagent. While this reaction sequence is viewed as classic, recently, while attempting to synthesize several glutaconic acid derivatives, we observed great difficulty isolating ...

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