Synthesis, anticancer and antioxidant activities of 7-methoxyisoflavanone and 2, 3-diarylchromanones

K Kanagalakshmi, M Premanathan, R Priyanka…

Index: Kanagalakshmi, Kanagasabai; Premanathan, Mariappan; Priyanka, Ragunathan; Hemalatha, Balasubramanian; Vanangamudi, Arumugasamy European Journal of Medicinal Chemistry, 2010 , vol. 45, # 6 p. 2447 - 2452

Full Text: HTML

Citation Number: 21

Abstract

A convenient, fast and high yielding method for the preparation of 7-methoxyisoflavanone and 2, 3-diarylchromanones has been developed by the condensation of benzyl-2-hydroxy- 4-alkoxyphenylketone with arylaldehyde/paraformaldehyde in presence of diethylamine, assisted by microwave activation. All the synthesized compounds were screened for anticancer as well as antioxidant activities. Among the nine compounds, 7- ...