Gold (I) Iodide catalyzed sonogashira reactions

P Li, L Wang, M Wang, F You

Index: Li, Pinhua; Wang, Lei; Wang, Min; You, Feng European Journal of Organic Chemistry, 2008 , # 35 p. 5946 - 5951

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Citation Number: 45

Abstract

Abstract Gold (I) iodide catalyzed Sonogashira reactions have been developed. Terminal alkynes reacted with aryl iodides and bromides smoothly in the presence of AuI (1 mol-%) and dppf (1 mol-%) in toluene to generate the corresponding cross-coupling products in good to excellent yields. Furthermore, aromatic terminal alkynes could also react with 2- iodoaniline to form substituted indoles in excellent yields through a coupling–cyclization ...

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