Tetrahedron

A general strategy for the synthesis of difluoromethyl-containing pyrazoles, pyridines and pyrimidines

…, K Vlach, M Vilches-Herrera, D Ostrovskyi, S Mkrtchyan…

Index: Iaroshenko, Viktor O.; Specowius, Verena; Vlach, Katharina; Vilches-Herrera, Marcelo; Ostrovskyi, Dmytro; Mkrtchyan, Satenik; Villinger, Alexander; Langer, Peter Tetrahedron, 2011 , vol. 67, # 31 p. 5663 - 5677

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Citation Number: 14

Abstract

Abstract Difluoromethyl-containing heteroannulated pyridines, pyrimidines and pyrazoles are prepared by a two step method. The regioselective cyclizations of electron-excessive aminoheterocycles, hydrazines and amidines with CF 2 Cl-substituted 1, 3-dicarbonyl ...