The Two Pathways for Effective Orthogonal Protection of L-Ornithine, for Amino Acylation of 5'-O-Pivaloyl Nucleosides, Describe the General and Important Role for …

SG Bayryamov, NG Vassilev…

Index: Bayryamov, Stanislav G.; Vassilev, Nikolay G.; Petkov, Dimiter D. Protein and Peptide Letters, 2010 , vol. 17, # 7 p. 889 - 898

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Abstract

Bz (NO2)-Orn (Boc)-OCH2CN was synthesized as an amino acid component with effective and successful orthogonal protection for amino acylation of 5'-O-Pivaloyl nucleosides and preparation of substrates for model ribosome reactions. The synthesis was carried out using suitable combinations of the methods of peptide synthesis and modification of amino acids.