Organic letters

N-Indolyltriethylborate: A Useful Reagent for Synthesis of C3-Quaternary Indolenines

A Lin, J Yang, M Hashim

Index: Lin, Aijun; Yang, Jiong; Hashim, Mohamed Organic Letters, 2013 , vol. 15, # 8 p. 1950 - 1953

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Citation Number: 30

Abstract

N-Indolyltriethylborate was found to be a useful reagent for dearomatizing C3-alkylation of 3- substituted indoles with both activated and nonactivated alkyl halides to give C3-quaternary indolenines, pyrroloindolines, furoindoline, and hexahydropyridoindoline under mild reaction conditions. The utility of these reagents was demonstrated in the syntheses of a pyrroloindoline-4-cholestene hybrid and debromoflustramine B.

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