A general and efficient synthesis of sulfonylbenzotriazoles from N-chlorobenzotriazole and sulfinic acid salts

AR Katritzky, V Rodriguez-Garcia…

Index: Katritzky, Alan R.; Rodriguez-Garcia, Valerie; Nair, Satheesh K. Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 1849 - 1852

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Citation Number: 44

Abstract

One-pot reactions of sulfinic acid salts (produced from organometallic reagents with SO2) with N-chlorobenzotriazole gave the corresponding N-alkane-, N-arene-, and N- heteroenesulfonylbenzotriazoles 3a-j in 41-93% yields. Reagents 3a-j are efficient sulfonylating agents, reacting at 20-80° C with various primary and secondary aliphatic amines to yield the corresponding sulfonamides in 64-100% yields.