Tetrahedron

Synthesis of biaryls via cross-coupling reaction of arylboronic acids with aryl chlorides catalyzed by NiCl 2/triphenylphosphine complexes

K Inada, N Miyaura

Index: Inada, Kaoru; Miyaura, Norio Tetrahedron, 2000 , vol. 56, # 44 p. 8657 - 8660

Full Text: HTML

Citation Number: 93

Abstract

The cross-coupling reaction of tolylboronic acids (1.3 equiv.) with chloroarenes in toluene was carried out at 80–100° C in the presence of a NiCl2/PPh3 catalyst (3mol%) and K3PO4· nH2O (2.6 equiv.). The reaction can be applied to various electron-deficient and-rich chloroarenes and is economical as the industrial process.

Related Articles:

Reusable and Sustainable Nanostructured Skeleton Catalyst: Heck Reaction with Nanoporous Metallic Glass Pd (PdNPore) as a Support, Stabilizer and Ligand??Free …

[Tanaka, Shinya; Kaneko, Tetsuro; Asao, Naoki; Yamamoto, Yoshinori; Chen, Mingwei; Zhang, Wei; Inoue, Akihisa Chemical Communications, 2011 , vol. 47, # 21 p. 5985 - 5987]

A base-free, one-pot diazotization/cross-coupling of anilines with arylboronic acids

[Mo, Fanyang; Qiu, Di; Jiang, Yubo; Zhang, Yan; Wang, Jianbo Tetrahedron Letters, 2011 , vol. 52, # 4 p. 518 - 522]

tert-Butoxide-mediated arylation of benzene with aryl halides in the presence of a catalytic 1, 10-phenanthroline derivative

[Shirakawa, Eiji; Itoh, Ken-Ichi; Higashino, Tomohiro; Hayashi, Tamio Journal of the American Chemical Society, 2010 , vol. 132, # 44 p. 15537 - 15539]

Plasmonic harvesting of light energy for Suzuki coupling reactions

[Wang, Feng; Li, Chuanhao; Chen, Huanjun; Jiang, Ruibin; Sun, Ling-Dong; Li, Quan; Wang, Jianfang; Yu, Jimmy C.; Yan, Chun-Hua Journal of the American Chemical Society, 2013 , vol. 135, # 15 p. 5588 - 5601]

Palladium-catalyzed Hiyama cross-coupling reactions of aryl mesylates

[Zhang, Liang; Qing, Jiang; Yang, Pengyuan; Wu, Jie Organic Letters, 2008 , vol. 10, # 21 p. 4971 - 4974]

More Articles...