A one-pot efficient and fast Hiyama coupling using palladium nanoparticles in water under fluoride-free conditions
BC Ranu, R Dey, K Chattopadhyay
Index: Ranu, Brindaban C.; Dey, Raju; Chattopadhyay, Kalicharan Tetrahedron Letters, 2008 , vol. 49, # 21 p. 3430 - 3432
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Citation Number: 60
Abstract
An efficient Hiyama cross-coupling of a wide variety of substituted aryl bromides and iodides with arylsilanes has been achieved at 100° C in water through a simple one-pot operation using in situ generated palladium nanoparticles. This reaction is very fast (5min) and has been performed in air under fluoride-free conditions, giving excellent chemoselectivity and high yields.
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