A “catch and release” strategy for the parallel synthesis of 2, 4, 5-trisubstituted pyrimidines

A Porcheddu, G Giacomelli, L De Luca…

Index: Hegarty,A.F. et al. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1973 , p. 2054 - 2060

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Citation Number: 31

Abstract

... Journal of Combinatorial ... its salt with sodium ethoxide in boiling EtOH/THF (4/1) for 2 h resulted in the formation of the chemically pure target ... Pyrimidines were obtained in both good yield and chemical purity (between 85 and 92%, as judged by HPLC−UV 254/MS measurements ...