The Synthesis of Some Alkyl and Dialkylaminoalkyl Esters of 2-Nitro-5-fluorobenzoic Acid and 2-Amino-5-fluorobenzoic Acid

LS Fosdick, RQ Blackwell

Index: Fosdick; Blackwell Journal of the American Chemical Society, 1944 , vol. 66, p. 1165

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Citation Number: 7

Abstract

Recently it was found'that certain alkamine esters of p-fluoro-and of 3-amino-4-fluorobenzoic acid produce excellent anesthesia, both by injection and by topical application to mucous membrane. Although some of them are less toxic than procaine, they cause local tissue irritation and are unstable in solution.