Influence of external ligands and auxiliaries on the reactivity of low-valent titanium in McMurry reaction: Selectivity and mechanistic profile

N Balu, SK Nayak, A Banerji

Index: Balu; Nayak; Banerji Journal of the American Chemical Society, 1996 , vol. 118, # 25 p. 5932 - 5937

Full Text: HTML

Citation Number: 50

Abstract

Influence of various external ligands/auxiliaries on the reductive carbonyl coupling reactions mediated by low-valent titanium (LVT) reagents (McMurry coupling) has been explored. The LVT species generated from Tyrlik's TiCl3-Mg-THF system has been selected for the reactivity-tuning trials. Our studies show that incorporation of about 10 equiv of pyridine (a π- acceptor ligand) with respect to TiCl3 to the THF solvated LVT reagent could arrest the ...

Related Articles:

A facile two-step synthesis of 2-arylbenzofurans based on the selective cross McMurry couplings

[Duan, Xin-Fang; Zeng, Jing; Lue, Jia-Wei; Zhang, Zhan-Bin Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9873 - 9876]

Unprecedented reductive dealkoxylation of aryl alkyl ethers and intramolecular C–C coupling of 2, 2′-dialkoxystilbenes with low valent titanium: one-pot synthesis of …

[Banerji, Asoke; Nayak, Sandip, K. Journal of the Chemical Society, Chemical Communications, 1991 , # 20 p. 1432 - 1434]

Cyclopropyl Analogs of Hexestrol and Diethylstilbestrol1, 2

[Bennett,J.G.; Bunce,S.C. Journal of Organic Chemistry, 1960 , vol. 25, p. 73 - 79]

More Articles...