Nature Immunology 2017-07-19

Untangling Fc and complement receptors to kill tumors

Cees E van der Poel, Michael C Carroll

Index: 10.1038/ni.3797

Full Text: HTML

Abstract

Uncoupling of activation of Fc receptors via a mutant IgG1 Fc domain shows a direct role for complement receptors in antibody-dependent tumor killing.

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