The Journal of organic chemistry

Dissecting the Complex Recognition Interfaces of Potent Tetrazole-and Pyrrole-Based Anion Binders

T Pinter, C Simhadri, F Hof

Index: Pinter, Thomas; Simhadri, Chakravarthi; Hof, Fraser Journal of Organic Chemistry, 2013 , vol. 78, # 10 p. 4642 - 4648

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Citation Number: 6

Abstract

Tetrazoles are potent anion binders. We report here a new family of tetrazole–pyrrole–amide hosts that arise when a tetrazole is incorporated as a new binding element alongside the well-known amidopyrrole anion-binding scaffold. In addition to reporting three new, modular synthetic routes that can be used to access these structures, we also report that the new hosts are highly potent binders of chloride. Along the way, we carried out studies of a ...