Synthesis

Condensation of Conjugated Enones With Diethyl Aminomalonate: A New and Convenient Access to 2, 2-Bis (ethoxycarbonyl)-3, 4-dihydro-2H-pyrroles

GB Itoua, JY Laronze

Index: Itoua, Gaston Bedel; Laronze, Jean-Yves Synthesis, 1987 , # 4 p. 353 - 357

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Abstract

2, 2-Bis-(cthoxycarbonyl)-3, 4-dihydro-2H-pyrroles are prepared from conjugated enones and diethyl aminomalonate by a one-step cyclocon-densation reaction. Reduction of the products with sodium cyanobo-rohydride affords the corresponding pyrrolidines. Pyrrole-2-

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